EO Bioeconomy Theme:

Human Health


In the ever-evolving landscape of human health, the challenges we face today are as diverse as they are complex. Alongside the rise of chronic diseases and global pandemics is the growing need for realizing personalized medicine, personalized prevention, and sustainable healthcare solutions.  We urgently need to innovate in the field of human health. These challenges present not only obstacles but also immense opportunities for the research and development (R&D) community to make groundbreaking contributions to increase productivity, lower healthcare costs, and improve overall quality of life. These opportunities will hopefully allow us to provide a systematic understanding of biotechnology products and a potential to impact public health.

Human Health Logo

Advancing human health outcomes through innovative R&D across the full health continuum.

The realm of human health R&D is vast and multifaceted, encompassing areas such as biomedical research, public health studies, pharmaceutical development, medical technology, and healthcare delivery models. Scientists, engineers, and healthcare professionals are at the forefront of this endeavor, working to uncover new insights into living systems and human biology, develop life-saving treatments and technologies, and improve healthcare systems globally.

Call to Action

The CASA-Bio initiative was created to help implement the Bioeconomy Executive Order issued by the White House in September 2022. The EO laid out a vision for government-wide collaboration to advance biotechnology and biomanufacturing through foundational and use-inspired research in five thematic areas: climate change, food and agriculture, supply chain resilience, human health, and the cross-cutting advances. The goal of CASA-Bio is to bring the EO to life.

The first step in the CASA-Bio Action Plan was a set of so-called Alignment Meetings held in December 2023 in which representatives from government funding agencies, industries, and non-profits met and collaborated to identify scientific subthemes of shared interest—within each of the Bioeconomy Executive Order Themes--that we believe have high potential to advance the bioeconomy through

innovative R&D. Now, it is time for step two. We invite you, the research community, to view these subthemes and consider how your research ideas could contribute. Your input will serve to help us define synergistic priority research areas that will be subjects of future research community workshops and development of road maps for addressing key challenges to advance the bioeconomy.

This scenario is not just a professional opportunity; it's a global imperative. As members of the R&D community, there's a call to action to apply your knowledge, skills, and creativity to address the pressing health challenges of our time. Whether your expertise is in genetics, bioengineering, pharmacology, data science, or any other field, your contributions can lead to significant advancements in health (i.e., reduce disease burden) and medicine.

Your work has the potential to revolutionize how we understand and treat diseases, enhance the effectiveness and accessibility of healthcare, and ultimately improve the quality and longevity of life. The development of new vaccines, personalized therapies, advanced diagnostic tools, and efficient healthcare systems are just a few examples of the impactful outcomes your research can achieve. Now is the time to harness the power of innovation to drive forward advances in human health. The collaborative efforts of the R&D community can lead to transformative changes. Join this critical mission to advance human health, where your contributions can make a profound difference in the lives of millions and shape a healthier future for all.

Representative Subtheme Challenges:

New approaches are needed to design vaccines and biologics with features that offer broader protection, greater supply chain resilience, simpler routes of administration, and lower costs.
Advances in computing technologies and accessibility are needed to help integrate different types of health data for diagnosis and treatment planning, while preserving patient privacy.
New research and infrastructure, spanning from traditional farming and food production to sustainable biotechnologies, are needed to improve human nutrition and enhanced well-being.
A more expansive view of public health is needed to ensure that biotechnology innovations broadly benefit humans, animals and plants that serve as food, and the environment.
Both basic and applied research investments are needed to improve many aspects of cell therapy, including cell sourcing, manufacturing, reproducibility, and costs.
New technologies like at-home diagnostic tools and smart wearables for disease detection hold great promise, but additional research into these tools is needed to evaluate effectiveness.
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CASA-Bio is based upon work supported by the U.S. National Science Foundation under Contract No. 49100423P0058. Any opinions, findings and conclusions or recommendations expressed in this material do not necessarily reflect the views of the U.S. National Science Foundation.
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